STIs During Pregnancy: What Every Parent Should Know

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Key takeaway: Some STIs can be passed from a pregnant person to their baby during pregnancy or childbirth. However, most congenital infections are preventable with early screening and timely treatment.

Did you know that sexually transmitted infections (STIs) can be passed from a pregnant person to their unborn baby?

Many people assume STIs are only transmitted through sexual contact, but in fact, some STIs can lead to congenital infections — where the infection is passed to the fetus during pregnancy or childbirth.

These infections can cause serious complications, such as stillbirth, neonatal death, neurological damage, and vision or hearing loss.

What Is a Congenital STI?

A congenital STI occurs when a pregnant individual with an STI transmits the infection to the fetus, either during pregnancy through the placenta or during childbirth via the birth canal.

The good news is that most congenital infections are preventable with early diagnosis and appropriate treatment.

Female gynecologist with tablet

Common STIs That Can Be Transmitted to Newborns

1. Syphilis

  • Transmission: Through the placenta during pregnancy
  • Potential impact: Miscarriage, stillbirth, preterm birth, low birth weight, congenital abnormalities, neurological damage, meningitis, enlarged liver

2. Chlamydia

  • Transmission: Through the birth canal during delivery
  • Potential impact: Newborn conjunctivitis, pneumonia
  • In mothers: increased risk of ectopic pregnancy and pelvic inflammatory disease (PID)

3. Gonorrhea

  • Transmission: During vaginal delivery
  • Potential impact: Conjunctivitis in newborns, which may lead to vision damage or blindness
  • In mothers: risk of uterine infection and preterm labor

4. HIV (Human Immunodeficiency Virus)

  • Transmission: During pregnancy, delivery, or breastfeeding
  • Potential impact: Congenital HIV infection, weakened immune system, delayed growth, long-term health complications

When Should STI Testing Be Done During Pregnancy?

Test Type Recommended Screening Time Recommended Rescreening Time
Syphilis Early pregnancy + at 28 weeks + at delivery Every trimester for high-risk pregnant individuals
Chlamydia, Gonorrhea Early pregnancy Third trimester for high-risk pregnant individuals
HIV Early pregnancy Third trimester for high-risk pregnant individuals

Testing Timeline reference:

  • First trimester: Weeks 1–13
  • Second trimester: Weeks 14–27
  • Third trimester: Weeks 28–delivery

Regular prenatal STI testing is the most reliable way to detect infections early and prevent complications for both mother and baby.

Tips for Preventing STIs During Pregnancy

  • Get tested for STIs with your partner
  • Practice safer sex by using condoms consistently
  • Seek medical attention if you notice abnormal discharge, itching, or other symptoms
  • Get a full health screening before trying to conceive

STIs during pregnancy can affect the mother and the health of the baby. Fortunately, most infections are completely preventable with routine prenatal screening and timely treatment.

Doctor examining pregnant woman

Medical Disclaimer: This article is for educational purposes only and does not constitute medical advice. Pregnant individuals should consult with their healthcare provider about appropriate screening, testing, and prenatal care. At-home collection test kits are a screening tool; positive results require confirmation and treatment from a healthcare provider. If you are experiencing a medical emergency, call 911.

HS
Medically Reviewed by: Honggang Shen, MD
Last Updated: July 25, 2025